2021 Eurasc Symposium

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After a general presentation of the Horizon Europe FP9 programme, the 2021 EURASC Symposium will be dedicated to the increasing roles of micro- and nanotechnologies for medicine and life sciences.

This will be illustrated by many examples: nanoparticles for drug delivery and as a tool to escape multidrug resistance in cancer, nano-sized recombinant viruses for gene therapy, nano-engines such as the CRSPR-Cas9 complex which is in the way to revolutionize precision medicine by allowing precise genome editing.

In addition, micrometer sized cells, which have been genetically modified by using nanometric recombinant viruses, have proved successful for numerous rare disorders, such as those of the immune system, or beta-thalassemia. Such gene/cell therapies represent also one of the most exciting recent breakthroughs in cancer.

Strikingly, the very same nanolipid particles which had been originally developed to treat rare disease by using oligonucleotides or RNA-interfering genetic drugs, have been successfully used for the recent mRNA vaccines against COVID-19 and other viruses.

Prestigious invited speakers will describe these dramatic advances and will also detail how mathematical epidemiological models can be implemented for the control of the COVID-19 pandemic. In the final presentation, ethical considerations for biomedicine will be presented and discussed.

9:30 Opening speeches
9:50 Mr. Jean-Eric Paquet, European Commission, Director-General, DG Research and Innovation
Horizon Europe FP9
10:30 Pr. Elias Fattal, University Paris-OrsayPharmacy FacultyGalien Institute
Nanomedicine for tackling physiological resistances to drug delivery
11:10 Pr. Stefaan de Smet, Ghent University, EURASC
Physico-Chemistry of nanoparticles for drug delivery
11:50 Dr. Carine Giovannangeli, CNRS – National Museum of Natural History
Genome editing with CRISPR-Cas nucleases
12:30 Pause
14:00 Dr. Ana Buj-Bello, Généthon Laboratory, Inserm
Gene therapy of neuromuscular disorders with viral-derived vectors
14:40 Pr. Daniel Scherman, Foundation for Rare Diseases, Pharmacy Faculty, Paris University, CNRS, Inserm, EURASC
Genetic Pharmacology: RNA-silencing nanoparticles and targeted nanodrugs for rare diseases
15:20 Pr. Odile Launay, Haut Conseil de la Santé Publique, Professor of Infectiology Hôpital Cochin-Broca-Hôtel-Dieu
Strategies of COVID-19 vaccination
16:00 Pr. Neil Ferguson, Imperial College, London
Modelling of the Covid-19 pandemic. Connections with computational science, mathematical epidemiology, and control and vaccination policy making
16:40 Pr. Alain Fischer, Imagine Institute, Necker Hospital, French Academy of Sciences and Academy of Medicine
Gene therapy of severe immune rare diseases
17:20 Dr. Hervé Chneiweiss Inserm, Président od Inserm Ethics Committee and of CCNE (Comité Consultatif National d’Ethique pour les sciences de la vie et de la santé)
Ethical considerations in Biomedicine
18:00 Closure of the scientific day